Epidermal Lipoxygenase Products of the Hepoxilin Pathway Selectively Activate the Nuclear Receptor P...
Epidermal Lipoxygenase Products of the Hepoxilin Pathway Selectively Activate the Nuclear Receptor PPARα
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Publisher
Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
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Language
English
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Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
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Contents
Arachidonic acid can be transformed into a specific epoxyalcohol product via the sequential action of two epidermal lipoxygenases, 12R-LOX and eLOX3. Functional impairment of either lipoxygenase gene (ALOX12B or ALOXE3) results in ichthyosis, suggesting a role for the common epoxyalcohol product or its metabolites in the differentiation of normal h...
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Full title
Epidermal Lipoxygenase Products of the Hepoxilin Pathway Selectively Activate the Nuclear Receptor PPARα
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TN_cdi_proquest_journals_2666539689
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2666539689
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ISSN
0024-4201
E-ISSN
1558-9307
DOI
10.1007/s11745-007-3054-4
