Pentacyclic triterpenoid ursolic acid induces apoptosis with mitochondrial dysfunction in adult T-ce...
Pentacyclic triterpenoid ursolic acid induces apoptosis with mitochondrial dysfunction in adult T-cell leukemia MT-4 cells to promote surrounding cell growth
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New York: Springer US
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English
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New York: Springer US
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We investigated the antitumor effects of oleanolic acid (OA) and ursolic acid (UA) on adult T-cell leukemia cells. OA and UA dose-dependently inhibited the proliferation of adult T-cell leukemia cells. UA-treated cells showed caspase 3/7 and caspase 9 activation. PARP cleavage was detected in UA-treated MT-4 cells. Activation of mTOR and PDK-1 was...
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Pentacyclic triterpenoid ursolic acid induces apoptosis with mitochondrial dysfunction in adult T-cell leukemia MT-4 cells to promote surrounding cell growth
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TN_cdi_proquest_journals_2674139240
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2674139240
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ISSN
1559-131X,1357-0560
E-ISSN
1559-131X
DOI
10.1007/s12032-022-01707-x
