The Future of Seed Amplification Assays and Clinical Trials
The Future of Seed Amplification Assays and Clinical Trials
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Publisher
Lausanne: Frontiers Research Foundation
Journal title
Language
English
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Publisher
Lausanne: Frontiers Research Foundation
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Scope and Contents
Contents
Prion-like seeded misfolding of host proteins is the leading hypothesised cause of neurodegenerative diseases. The exploitation of the mechanism in the protein misfolding cyclic amplification (PMCA) and real-time quaking-induced conversion (RT-QuIC) assays have transformed prion disease research and diagnosis and have steadily become more widely us...
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Full title
The Future of Seed Amplification Assays and Clinical Trials
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TN_cdi_proquest_journals_2679442843
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2679442843
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ISSN
1663-4365
E-ISSN
1663-4365
DOI
10.3389/fnagi.2022.872629
