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Breast cancer chemotherapy induces vascular dysfunction and hypertension through a NOX4- dependent m...

Breast cancer chemotherapy induces vascular dysfunction and hypertension through a NOX4- dependent m...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2684620653

Breast cancer chemotherapy induces vascular dysfunction and hypertension through a NOX4- dependent mechanism

About this item

Full title

Breast cancer chemotherapy induces vascular dysfunction and hypertension through a NOX4- dependent mechanism

Publisher

Ann Arbor: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2022-07, Vol.132 (13), p.1-18

Language

English

Formats

Publication information

Publisher

Ann Arbor: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Cardiovascular disease is the major cause of morbidity and mortality in breast cancer survivors. Chemotherapy contributes to this risk. We aimed to define the mechanisms of long-term vascular dysfunction caused by neoadjuvant chemotherapy (NACT) and identify novel therapeutic targets. We studied arteries from postmenopausal women who had undergone...

Alternative Titles

Full title

Breast cancer chemotherapy induces vascular dysfunction and hypertension through a NOX4- dependent mechanism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2684620653

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2684620653

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCM49117.

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