Single-cell CD8+ dynamics in PLWH uncover the depletion of TIGIT+ memory HIV-1-specific cells during...
Single-cell CD8+ dynamics in PLWH uncover the depletion of TIGIT+ memory HIV-1-specific cells during long-term ART
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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The expression of inhibitory receptors (IRs) is a hallmark of CD8+ T-cell exhaustion (Tex) in people living with HIV-1 (PLWH). Understanding the dynamics of IRs expression in PLWH on long-term antiretroviral treatment (ART) is critical to overcoming CD8+ Tex and designing broadly applicable HIV-1 immunotherapies for cure. To address this, we combin...
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Single-cell CD8+ dynamics in PLWH uncover the depletion of TIGIT+ memory HIV-1-specific cells during long-term ART
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TN_cdi_proquest_journals_2689387301
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2689387301
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DOI
10.1101/2022.07.13.499924
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https://www.proquest.com/docview/2689387301?pq-origsite=primo&accountid=13902
