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TREK-1 knock-down in human atrial fibroblasts leads to a myofibroblastic phenotype: a role in phenoc...

TREK-1 knock-down in human atrial fibroblasts leads to a myofibroblastic phenotype: a role in phenoc...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2692864522

TREK-1 knock-down in human atrial fibroblasts leads to a myofibroblastic phenotype: a role in phenoconversion and overview of mechano-sensitive channel mRNA expression in cardiac diseases

About this item

Full title

TREK-1 knock-down in human atrial fibroblasts leads to a myofibroblastic phenotype: a role in phenoconversion and overview of mechano-sensitive channel mRNA expression in cardiac diseases

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2022-07

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Cardiac cell mechanical environment changes on a beat-by-beat basis and also in the course of various cardiac diseases. Cells sense and adapt to such mechanical cues via specialized mecha-no-sensors mediating adaptive signaling cascades. Here, we report TREK-1 mRNA expression and activity in human atrial fibroblasts and reveal a cross talk between...

Alternative Titles

Full title

TREK-1 knock-down in human atrial fibroblasts leads to a myofibroblastic phenotype: a role in phenoconversion and overview of mechano-sensitive channel mRNA expression in cardiac diseases

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2692864522

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2692864522

Other Identifiers

DOI

10.1101/2022.07.21.492231