Interfering with nucleotide excision by the coronavirus 3'-to-5' exoribonuclease
Interfering with nucleotide excision by the coronavirus 3'-to-5' exoribonuclease
About this item
Full title
Author / Creator
Publisher
United States: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publication information
Publisher
United States: Cold Spring Harbor Laboratory Press
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More information
Scope and Contents
Contents
Some of the most efficacious antiviral therapeutics are ribonucleos(t)ide analogs. The presence of a 3'-to-5' proofreading exoribonuclease (ExoN) in coronaviruses diminishes the potency of many ribonucleotide analogs. The ability to interfere with ExoN activity will create new possibilities for control of SARS-CoV-2 infection. ExoN is formed by a 1...
Alternative Titles
Full title
Interfering with nucleotide excision by the coronavirus 3'-to-5' exoribonuclease
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2700908946
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2700908946
Other Identifiers
ISSN
2692-8205
E-ISSN
2692-8205
DOI
10.1101/2022.08.11.503614
