Biological evaluation, molecular modeling and dynamics simulation of phenanthrenes isolated from Ble...
Biological evaluation, molecular modeling and dynamics simulation of phenanthrenes isolated from Bletillastriata as butyrylcholinesterase inhibitors
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Author / Creator
Liu, Yi , Tu, Yanbei , Kang, Yunyao , Zhu, Chao , Wu, Chuanhai , Chen, Gang , Liu, Zerong and Li, Yanfang
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
As part of our continuous studies on natural cholinesterase inhibitors from plant kingdom, the 95% ethanol extract from tubers of
Bletilla
striata
showed promising butyrylcholinesterase (BChE) inhibition (IC
50
= 8.6 μg/mL). The extracts with different polarities (petroleum ether, ethyl acetate, n-butanol, and water) were prepared a...
Alternative Titles
Full title
Biological evaluation, molecular modeling and dynamics simulation of phenanthrenes isolated from Bletillastriata as butyrylcholinesterase inhibitors
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Record Identifier
TN_cdi_proquest_journals_2700915868
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2700915868
Other Identifiers
E-ISSN
2045-2322
DOI
10.1038/s41598-022-17912-7
