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A Simplified Function-First Method for the Discovery and Optimization of Bispecific Immune Engaging...

A Simplified Function-First Method for the Discovery and Optimization of Bispecific Immune Engaging...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2703665861

A Simplified Function-First Method for the Discovery and Optimization of Bispecific Immune Engaging Antibodies

About this item

Full title

A Simplified Function-First Method for the Discovery and Optimization of Bispecific Immune Engaging Antibodies

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2022-08

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Bi-specific T-cell engager antibodies (BITEs) are synthetic soluble molecules derived from antibodies that induce active contact between T-cells and other target cells in the body. BITE therapeutics have shown great promise for the treatment of various forms of cancer; however, the current development process for BITEs is time consuming and costly....

Alternative Titles

Full title

A Simplified Function-First Method for the Discovery and Optimization of Bispecific Immune Engaging Antibodies

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2703665861

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2703665861

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2022.08.17.504342