Sex-specific T cell exhaustion drives differential immune responses in glioblastoma
Sex-specific T cell exhaustion drives differential immune responses in glioblastoma
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Author / Creator
Lee, Juyeun , Nicosia, Michael , Silver, Daniel J , Li, Cathy , Bayik, Defne , Watson, Dionysios C , Lauko, Adam , Johnson, Sadie , Mcgraw, Mary , Grabowski, Matthew , Kish, Danielle , Desai, Amar , Goodman, Wendy , Cameron, Scott , Okada, Hideho , Valujskikh, Anna , Fairchild, Robert L , Ahluwalia, Manmmet S and Lathia, Justin D
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Scope and Contents
Contents
Sex differences in glioblastoma (GBM) incidence and outcome are well recognized, and emerging evidence suggests that these extend to genetic/epigenetic and cellular differences, including immune responses. However, the mechanisms driving immunological sex differences are not fully understood. Using GBM models, we demonstrate that T cells play a cri...
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Full title
Sex-specific T cell exhaustion drives differential immune responses in glioblastoma
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TN_cdi_proquest_journals_2703669511
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2703669511
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2022.08.17.503211
How to access this item
https://www.proquest.com/docview/2703669511?pq-origsite=primo&accountid=13902
