IDDF2022-ABS-0088 Peptostreptococcus anaerobius drives immune suppression and immune therapy resista...
IDDF2022-ABS-0088 Peptostreptococcus anaerobius drives immune suppression and immune therapy resistance in colorectal cancer
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London: BMJ Publishing Group Ltd and British Society of Gastroenterology
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English
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London: BMJ Publishing Group Ltd and British Society of Gastroenterology
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BackgroundThe gut microbiome plays a crucial role in cancer progression and treatment through shaping the tumor immune microenvironment (TIME). Here, we investigated the effect of P. anaerobius on the TIME, its molecular mechanism of action, and the impact of P. anaerobius on the efficacy of immune checkpoint blockade (ICB) therapy.MethodsThe effec...
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IDDF2022-ABS-0088 Peptostreptococcus anaerobius drives immune suppression and immune therapy resistance in colorectal cancer
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TN_cdi_proquest_journals_2711022978
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2711022978
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ISSN
0017-5749
E-ISSN
1468-3288
DOI
10.1136/gutjnl-2022-IDDF.1