Co-aggregation with Apolipoprotein E modulates the function of Amyloid-β in Alzheimer's disease
Co-aggregation with Apolipoprotein E modulates the function of Amyloid-β in Alzheimer's disease
About this item
Full title
Author / Creator
Xia, Zengjie , Prescott, Emily , Wareing, Hollie E , Matuszyk, Martyna M , Dakin, Helen , Dimou, Eleni , Zuo, Eric , Zhang, Yu P , Lam, Jeff Y L , Danial, John S H , Tom, Leah , Barnes, Katy M , Strickland, Michael , Jiang, Hong , Thornton, Peter , Crowther, Damian C , Holtzman, David M , Bell, Simon M , Higginbottom, Adrian , Ferraiuolo, Laura , Mortiboys, Heather J , Wharton, Stephen B , Ranasinghe, Rohan T , Klenerman, David and De, Suman
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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More information
Scope and Contents
Contents
Which isoforms of apolipoprotein E (apoE) we inherit determine our risk of developing late-onset Alzheimer's Disease (AD), but the mechanism underlying this link is poorly understood. In particular, the relevance of direct interactions between apoE and amyloid-β (Aβ) remains controversial. Here, single-molecule imaging shows that all isoforms of ap...
Alternative Titles
Full title
Co-aggregation with Apolipoprotein E modulates the function of Amyloid-β in Alzheimer's disease
Authors, Artists and Contributors
Author / Creator
Prescott, Emily
Wareing, Hollie E
Matuszyk, Martyna M
Dakin, Helen
Dimou, Eleni
Zuo, Eric
Zhang, Yu P
Lam, Jeff Y L
Danial, John S H
Tom, Leah
Barnes, Katy M
Strickland, Michael
Jiang, Hong
Thornton, Peter
Crowther, Damian C
Holtzman, David M
Bell, Simon M
Higginbottom, Adrian
Ferraiuolo, Laura
Mortiboys, Heather J
Wharton, Stephen B
Ranasinghe, Rohan T
Klenerman, David
De, Suman
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2721470537
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2721470537
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2021.07.13.452239
How to access this item
https://www.proquest.com/docview/2721470537?pq-origsite=primo&accountid=13902
