TRB3 augments IL1β-TLR4 signaling by engaging Flightless-homolog 1
TRB3 augments IL1β-TLR4 signaling by engaging Flightless-homolog 1
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Signaling via IL1-beta and TLR4 receptors (IL1R-TLR4) plays a crucial role in cytokine and fatty acid-induced beta cell inflammation, in type 1 and type 2 diabetes respectively. IL1R-TLR4 share signaling mechanisms via a common, cytoplasmic, toll-like-receptor domain to activate proinflammatory JNK and IKK kinases. We have previously reported that...
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TRB3 augments IL1β-TLR4 signaling by engaging Flightless-homolog 1
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TN_cdi_proquest_journals_2723283791
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2723283791
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E-ISSN
2692-8205
DOI
10.1101/2022.10.09.511391
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https://www.proquest.com/docview/2723283791?pq-origsite=primo&accountid=13902
