O12 Hepatic parameters, growth, and sleep with responders and nonresponders to odevixibat treatment:...
O12 Hepatic parameters, growth, and sleep with responders and nonresponders to odevixibat treatment: pooled data from the PEDFIC 1 and PEDFIC 2 studies in children with progressive familial intrahepatic cholestasis
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McKiernan, Patrick , Sturm, Ekkehard , Kamath, Binita M , Thompson, Richard J , Gonzalès, Emmanuel , Lachaux, Alain , Baumann, Ulrich , Shteyer, Eyal , Czubkowski, Piotr , Artan, Reha , Dalgic, Buket , Özen, Hasan , Gupte, Girish , Grammatikopoulos, Tassos , Karpen, Saul J , Ni, Quanhong , Kjems, Lise and Horn, Patrick
Publisher
London: BMJ Publishing Group Ltd
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Language
English
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Publisher
London: BMJ Publishing Group Ltd
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Contents
Introduction/BackgroundProgressive familial intrahepatic cholestasis (PFIC) is a group of inherited paediatric cholestatic liver diseases. In the phase 3 PEDFIC 1 and PEDFIC 2 studies, odevixibat, an ileal bile acid transporter inhibitor, reduced serum bile acids (sBAs) and improved pruritus in patients with PFIC.AimUsing pooled data from PEDFIC 1...
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Full title
O12 Hepatic parameters, growth, and sleep with responders and nonresponders to odevixibat treatment: pooled data from the PEDFIC 1 and PEDFIC 2 studies in children with progressive familial intrahepatic cholestasis
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TN_cdi_proquest_journals_2723818802
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2723818802
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ISSN
2041-4137
E-ISSN
2041-4145
DOI
10.1136/flgastro-2022-bspghan.12
