A spatiotemporal map of the aging mouse brain reveals white matter tracts as vulnerable foci
A spatiotemporal map of the aging mouse brain reveals white matter tracts as vulnerable foci
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Aging is the key risk factor for loss of cognitive function and neurodegeneration but our knowledge of molecular dynamics across the aging brain is very limited. Here we perform spatiotemporal RNA-seq of mouse brain aging, encompassing 847 samples from 15 regions spanning 7 ages. We identify a brain-wide gene signature representing aging in glia wi...
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A spatiotemporal map of the aging mouse brain reveals white matter tracts as vulnerable foci
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TN_cdi_proquest_journals_2730173453
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2730173453
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E-ISSN
2692-8205
DOI
10.1101/2022.09.18.508419
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https://www.proquest.com/docview/2730173453?pq-origsite=primo&accountid=13902
