Identification of key residues of the DNA glycosylase OGG1 controlling efficient DNA scanning and re...
Identification of key residues of the DNA glycosylase OGG1 controlling efficient DNA scanning and recruitment to oxidized bases in living cells
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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The DNA-glycosylase OGG1 oversees the detection and clearance of the 7,8-dihydro-8-oxoguanine (8-oxoG), which is the most frequent form of oxidized base in the genome. This lesion is deeply buried within the double-helix and its detection requires careful inspection of the bases by OGG1 via a mechanism that remains only partially understood. By ana...
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Full title
Identification of key residues of the DNA glycosylase OGG1 controlling efficient DNA scanning and recruitment to oxidized bases in living cells
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TN_cdi_proquest_journals_2732074662
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2732074662
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E-ISSN
2692-8205
DOI
10.1101/2022.11.04.515179
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https://www.proquest.com/docview/2732074662?pq-origsite=primo&accountid=13902
