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RAD-TGTs: Measurement of cellular tensions via flow cytometry and DNA sequencing enabled by force-de...

RAD-TGTs: Measurement of cellular tensions via flow cytometry and DNA sequencing enabled by force-de...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2733788443

RAD-TGTs: Measurement of cellular tensions via flow cytometry and DNA sequencing enabled by force-dependent rupture and delivery of DNA tension probes

About this item

Full title

RAD-TGTs: Measurement of cellular tensions via flow cytometry and DNA sequencing enabled by force-dependent rupture and delivery of DNA tension probes

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2022-11

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Mechanical force is a key driver of cellular processes and is dysregulated in many diseases. Measuring cellular tensions to elucidate mechanotransduction pathways typically involves high-resolution but low throughput imaging of surfaces and arduous experimental preparation of materials. We present here Rupture and Deliver DNA-duplex based molecular...

Alternative Titles

Full title

RAD-TGTs: Measurement of cellular tensions via flow cytometry and DNA sequencing enabled by force-dependent rupture and delivery of DNA tension probes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2733788443

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2733788443

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2022.11.08.515662