Tumor-specific CD4 T cells instruct monocyte differentiation in pancreatic ductal adenocarcinoma
Tumor-specific CD4 T cells instruct monocyte differentiation in pancreatic ductal adenocarcinoma
About this item
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Scope and Contents
Contents
Pancreatic ductal adenocarcinoma (PDA) is a lethal malignancy resistant to immunotherapy. The pancreatic tumor microenvironment is shaped and maintained by myeloid cells that outnumber tumor cells. Here, using monocyte fate-mapping PDA mouse models and human tumor tissues, we identify monocytes give rise to most heterogeneous macrophage subpopulati...
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Full title
Tumor-specific CD4 T cells instruct monocyte differentiation in pancreatic ductal adenocarcinoma
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TN_cdi_proquest_journals_2734827497
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2734827497
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E-ISSN
2692-8205
DOI
10.1101/2022.11.09.515858
How to access this item
https://www.proquest.com/docview/2734827497?pq-origsite=primo&accountid=13902
