Role of Genetic Polymorphisms in Drug-Metabolizing Enzyme-Mediated Toxicity and Pharmacokinetic Resi...
Role of Genetic Polymorphisms in Drug-Metabolizing Enzyme-Mediated Toxicity and Pharmacokinetic Resistance to Anti-Cancer Agents: A Review on the Pharmacogenomics Aspect
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Cham: Springer International Publishing
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English
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Cham: Springer International Publishing
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The inter-individual differences in cancer susceptibility are somehow correlated with the genetic differences that are caused by the polymorphisms. These genetic variations in drug-metabolizing enzymes/drug-inactivating enzymes may negatively or positively affect the pharmacokinetic profile of chemotherapeutic agents that eventually lead to pharmac...
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Role of Genetic Polymorphisms in Drug-Metabolizing Enzyme-Mediated Toxicity and Pharmacokinetic Resistance to Anti-Cancer Agents: A Review on the Pharmacogenomics Aspect
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TN_cdi_proquest_journals_2736344335
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2736344335
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ISSN
0312-5963
E-ISSN
1179-1926
DOI
10.1007/s40262-022-01174-7