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A human neural crest model reveals the developmental impact of neuroblastoma-associated chromosomal...

A human neural crest model reveals the developmental impact of neuroblastoma-associated chromosomal...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2739270398

A human neural crest model reveals the developmental impact of neuroblastoma-associated chromosomal aberrations

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Early childhood tumours arise from transformed embryonic cells, which often carry large copy number alterations (CNA). However, it remains unclear how CNAs contribute to embryonic tumourigenesis due to a lack of suitable models. Here we employ female human embryonic stem cell (hESC) differentiation and single-cell transcriptome and epigenome analys...

Alternative Titles

Full title

A human neural crest model reveals the developmental impact of neuroblastoma-associated chromosomal aberrations

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2739270398

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2739270398

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2022.11.21.515753