Efficacy and Safety of Bepirovirsen in Chronic Hepatitis B Infection
Efficacy and Safety of Bepirovirsen in Chronic Hepatitis B Infection
About this item
Full title
Author / Creator
Yuen, Man-Fung , Lim, Seng-Gee , Plesniak, Robert , Tsuji, Keiji , Janssen, Harry L.A. , Pojoga, Cristina , Gadano, Adrian , Popescu, Corneliu P. , Stepanova, Tatyana , Asselah, Tarik , Diaconescu, Gheorghe , Yim, Hyung Joon , Heo, Jeong , Janczewska, Ewa , Wong, Alexander , Idriz, Nevin , Imamura, Michio , Rizzardini, Giuliano , Takaguchi, Koichi , Andreone, Pietro , Arbune, Manuela , Hou, Jinlin , Park, Sung Jae , Vata, Andrei , Cremer, Jennifer , Elston, Robert , Lukić, Tamara , Quinn, Geoff , Maynard, Lauren , Kendrick, Stuart , Plein, Helene , Campbell, Fiona , Paff, Melanie , Theodore, Dickens and B-Clear Study Group
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
In a phase 2 trial, bepirovirsen, an antisense oligonucleotide that targets all hepatitis B virus mRNAs, resulted in sustained loss of hepatitis B surface antigen and HBV DNA in 9 to 10% of participants with chronic HBV infection.
Alternative Titles
Full title
Efficacy and Safety of Bepirovirsen in Chronic Hepatitis B Infection
Authors, Artists and Contributors
Author / Creator
Lim, Seng-Gee
Plesniak, Robert
Tsuji, Keiji
Janssen, Harry L.A.
Pojoga, Cristina
Gadano, Adrian
Popescu, Corneliu P.
Stepanova, Tatyana
Asselah, Tarik
Diaconescu, Gheorghe
Yim, Hyung Joon
Heo, Jeong
Janczewska, Ewa
Wong, Alexander
Idriz, Nevin
Imamura, Michio
Rizzardini, Giuliano
Takaguchi, Koichi
Andreone, Pietro
Arbune, Manuela
Hou, Jinlin
Park, Sung Jae
Vata, Andrei
Cremer, Jennifer
Elston, Robert
Lukić, Tamara
Quinn, Geoff
Maynard, Lauren
Kendrick, Stuart
Plein, Helene
Campbell, Fiona
Paff, Melanie
Theodore, Dickens
B-Clear Study Group
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2739465073
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2739465073
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa2210027
