Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses
Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Pancreatic α-cells secrete glucagon, an insulin counter-regulatory peptide hormone critical for the maintenance of glucose homeostasis. Investigation of the function of human α-cells remains a challenge due to the lack of cost-effective purification methods to isolate high-quality α-cells from islets. Here, we use the reaction-based probe diacetyla...
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Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses
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TN_cdi_proquest_journals_2740677547
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2740677547
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E-ISSN
2692-8205
DOI
10.1101/2022.11.27.518097
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https://www.proquest.com/docview/2740677547?pq-origsite=primo&accountid=13902