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Trem2 Promotes Foamy Macrophage Lipid Uptake and Survival in Atherosclerosis

Trem2 Promotes Foamy Macrophage Lipid Uptake and Survival in Atherosclerosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2741124531

Trem2 Promotes Foamy Macrophage Lipid Uptake and Survival in Atherosclerosis

About this item

Full title

Trem2 Promotes Foamy Macrophage Lipid Uptake and Survival in Atherosclerosis

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2022-11

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Atherosclerotic plaque formation is driven by the continued expansion of cholesterol loaded foamy macrophages within the arterial intima. Foamy macrophages are primarily derived from newly recruited monocytes, but factors regulating monocyte specification toward foamy macrophage differentiation and prolonged survival in plaque remain poorly underst...

Alternative Titles

Full title

Trem2 Promotes Foamy Macrophage Lipid Uptake and Survival in Atherosclerosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2741124531

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2741124531

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2022.11.28.518255