FBXO42 activity is required to prevent mitotic arrest, spindle assembly checkpoint activation, and l...
FBXO42 activity is required to prevent mitotic arrest, spindle assembly checkpoint activation, and lethality in glioblastoma and other cancers
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Glioblastoma (GBM) is the most common and aggressive brain tumor in adults. To identify genes differentially required for the viability of GBM stem-like cells (GSCs), we performed functional genomic lethality screens comparing GSCs and control human neural stem cells. Among top scoring hits in a subset of GBM cells was the F-box-containing gene FBX...
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FBXO42 activity is required to prevent mitotic arrest, spindle assembly checkpoint activation, and lethality in glioblastoma and other cancers
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TN_cdi_proquest_journals_2743795006
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2743795006
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E-ISSN
2692-8205
DOI
10.1101/2022.11.29.518420
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https://www.proquest.com/docview/2743795006?pq-origsite=primo&accountid=13902
