An Autoimmune Transcriptional Circuit Driving Foxp3+ Regulatory T cell Dysfunction
An Autoimmune Transcriptional Circuit Driving Foxp3+ Regulatory T cell Dysfunction
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Autoimmune diseases, among the most common disorders of young adults, are mediated by genetic and environmental factors. While CD4+Foxp3+ regulatory T cells (Tregs) play a central role in preventing autoimmunity, the molecular mechanism underlying their dysfunction is unknown. Here, we performed comprehensive transcriptomic and epigenomic profiling...
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Full title
An Autoimmune Transcriptional Circuit Driving Foxp3+ Regulatory T cell Dysfunction
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TN_cdi_proquest_journals_2745489636
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2745489636
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E-ISSN
2692-8205
DOI
10.1101/2022.12.02.518871
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https://www.proquest.com/docview/2745489636?pq-origsite=primo&accountid=13902