Epidermal Lipoxygenase Products of the Hepoxilin Pathway Selectively Activate the Nuclear Receptor P...
Epidermal Lipoxygenase Products of the Hepoxilin Pathway Selectively Activate the Nuclear Receptor PPAR[alpha]
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Heidelberg: Springer Nature B.V
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English
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Heidelberg: Springer Nature B.V
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Arachidonic acid can be transformed into a specific epoxyalcohol product via the sequential action of two epidermal lipoxygenases, 12R-LOX and eLOX3. Functional impairment of either lipoxygenase gene (ALOX12B or ALOXE3) results in ichthyosis, suggesting a role for the common epoxyalcohol product or its metabolites in the differentiation of normal h...
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Epidermal Lipoxygenase Products of the Hepoxilin Pathway Selectively Activate the Nuclear Receptor PPAR[alpha]
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TN_cdi_proquest_journals_274652198
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_274652198
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ISSN
0024-4201
E-ISSN
1558-9307
