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Shift of the insoluble content of the proteome in aging mouse brain

Shift of the insoluble content of the proteome in aging mouse brain

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2754188031

Shift of the insoluble content of the proteome in aging mouse brain

About this item

Full title

Shift of the insoluble content of the proteome in aging mouse brain

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2022-12

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Aging and protein aggregation diseases are inextricably linked. During aging, cellular response to unfolded proteins are believed to decline which results in diminished protein homeostasis (proteostasis). Indeed, in model organisms, such as C. elegans, proteostatic decline with age has even been linked to the onset of aggregation of proteins in wil...

Alternative Titles

Full title

Shift of the insoluble content of the proteome in aging mouse brain

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2754188031

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2754188031

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2022.12.13.520290