Optimized CRISPR guide RNA library cloning reduces skew and enables more compact genetic screens
Optimized CRISPR guide RNA library cloning reduces skew and enables more compact genetic screens
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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The development of CRISPR genetic screening tools has improved functional genomics, as these tools enable precise genomic editing, provide broad access to genomic regions beyond protein-coding genes, and have fewer off-target effects than other functional genomics modalities, allowing for novel applications with smaller library sizes. Pooled functi...
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Optimized CRISPR guide RNA library cloning reduces skew and enables more compact genetic screens
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TN_cdi_proquest_journals_2757200908
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2757200908
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E-ISSN
2692-8205
DOI
10.1101/2022.12.22.521524
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https://www.proquest.com/docview/2757200908?pq-origsite=primo&accountid=13902
