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Functional genomic analysis of adult and pediatric brain tumor isolates

Functional genomic analysis of adult and pediatric brain tumor isolates

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2761423085

Functional genomic analysis of adult and pediatric brain tumor isolates

About this item

Full title

Functional genomic analysis of adult and pediatric brain tumor isolates

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2023-01

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Background: Adult and pediatric tumors display stark differences in their mutation spectra and chromosome alterations. Here, we attempted to identify common and unique gene dependencies and their associated biomarkers among adult and pediatric brain tumor isolates using functional genetic lethal screens and computational modeling. Methods: We perfo...

Alternative Titles

Full title

Functional genomic analysis of adult and pediatric brain tumor isolates

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2761423085

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2761423085

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2023.01.05.522885