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The QseB response regulator imparts tolerance to positively charged antibiotics by controlling metab...

The QseB response regulator imparts tolerance to positively charged antibiotics by controlling metab...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2763952666

The QseB response regulator imparts tolerance to positively charged antibiotics by controlling metabolism and minor changes to LPS

About this item

Full title

The QseB response regulator imparts tolerance to positively charged antibiotics by controlling metabolism and minor changes to LPS

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2023-01

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

The modification of lipopolysaccharide (LPS) in Escherichia coli and Salmonella spp. is primarily controlled by the two-component system PmrAB. LPS modification allows bacteria to avoid killing by positively charged antibiotics like polymyxin B. We previously demonstrated that in uropathogenic E. coli (UPEC), the sensor histidine kinase PmrB also a...

Alternative Titles

Full title

The QseB response regulator imparts tolerance to positively charged antibiotics by controlling metabolism and minor changes to LPS

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2763952666

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2763952666

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2023.01.10.523522