Log in to save to my catalogue

Quantitative proteomic analysis reveals apoE4-dependent phosphorylation of the actin-regulating prot...

Quantitative proteomic analysis reveals apoE4-dependent phosphorylation of the actin-regulating prot...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2773994313

Quantitative proteomic analysis reveals apoE4-dependent phosphorylation of the actin-regulating protein VASP

About this item

Full title

Quantitative proteomic analysis reveals apoE4-dependent phosphorylation of the actin-regulating protein VASP

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2023-02

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Apolipoprotein (apo) E4 is the major genetic risk factor for Alzheimers Disease (AD). While neurons generally produce a minority of the apoE in the central nervous system, neuronal expression of apoE increases dramatically in response to stress and is sufficient to drive pathology. Currently, the molecular mechanisms of how apoE4 expression may reg...

Alternative Titles

Full title

Quantitative proteomic analysis reveals apoE4-dependent phosphorylation of the actin-regulating protein VASP

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2773994313

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2773994313

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2022.06.06.495052