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Accumulation of Tau in Extracellular Vesicles Disturbs the Astrocytic Mitochondrial System

Accumulation of Tau in Extracellular Vesicles Disturbs the Astrocytic Mitochondrial System

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2776862307

Accumulation of Tau in Extracellular Vesicles Disturbs the Astrocytic Mitochondrial System

About this item

Full title

Accumulation of Tau in Extracellular Vesicles Disturbs the Astrocytic Mitochondrial System

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2023-02

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Tauopathies are neurodegenerative disorders involving the accumulation of tau isoforms in cell subpopulations such as astrocytes. The origins of the 3R and 4R isoforms of tau that accumulate in astrocytes remain unclear. Extracellular vesicles (EVs) were isolated from primary neurons overexpressing 1N3R or 1N4R tau or from human brain extracts (pro...

Alternative Titles

Full title

Accumulation of Tau in Extracellular Vesicles Disturbs the Astrocytic Mitochondrial System

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2776862307

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2776862307

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2023.02.15.527595