Llama peripheral B-cell populations producing conventional and heavy chain-only IgG subtypes are phe...
Llama peripheral B-cell populations producing conventional and heavy chain-only IgG subtypes are phenotypically indistinguishable but immunogenetically distinct
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Contents
Camelid ungulates produce homodimeric heavy chain-only antibodies (
HCAbs
) in addition to conventional antibodies consisting of paired heavy and light chains. In the llama, HCAbs are made up by at least two subclasses (long-hinge IgG2b and short-hinge IgG2c HCAbs vs. conventional heterotetrameric IgG1s). Here, we generated murine monoclonal...
Alternative Titles
Full title
Llama peripheral B-cell populations producing conventional and heavy chain-only IgG subtypes are phenotypically indistinguishable but immunogenetically distinct
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TN_cdi_proquest_journals_2781400405
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2781400405
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ISSN
0093-7711
E-ISSN
1432-1211
DOI
10.1007/s00251-018-01102-9
