Distinct horizontal transfer mechanisms for type I and type V CRISPR-associated transposons
Distinct horizontal transfer mechanisms for type I and type V CRISPR-associated transposons
About this item
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Publisher
United States: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
United States: Cold Spring Harbor Laboratory Press
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Scope and Contents
Contents
CRISPR-associated transposons (CASTs) co-opt CRISPR-Cas proteins and Tn7-family transposons for RNA-guided vertical and horizontal transmission. CASTs encode minimal CRISPR arrays but can't acquire new spacers. Here, we show that CASTs instead co-opt defense-associated CRISPR arrays for horizontal transmission. A bioinformatic analysis shows that a...
Alternative Titles
Full title
Distinct horizontal transfer mechanisms for type I and type V CRISPR-associated transposons
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Record Identifier
TN_cdi_proquest_journals_2782551591
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2782551591
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ISSN
2692-8205
E-ISSN
2692-8205
DOI
10.1101/2023.03.03.531003
