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Octyl syringate is preferentially cytotoxic to cancer cells via lysosomal membrane permeabilization...

Octyl syringate is preferentially cytotoxic to cancer cells via lysosomal membrane permeabilization...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2791422480

Octyl syringate is preferentially cytotoxic to cancer cells via lysosomal membrane permeabilization and autophagic flux inhibition

About this item

Full title

Octyl syringate is preferentially cytotoxic to cancer cells via lysosomal membrane permeabilization and autophagic flux inhibition

Publisher

Dordrecht: Springer Netherlands

Journal title

Cell biology and toxicology, 2023-02, Vol.39 (1), p.183-199

Language

English

Formats

Publication information

Publisher

Dordrecht: Springer Netherlands

More information

Scope and Contents

Contents

The autophagy-mediated lysosomal pathway plays an important role in conferring stress tolerance to tumor cells during cellular stress such as increased metabolic demands. Thus, targeted disruption of this function and inducing lysosomal cell death have been proved to be a useful cancer therapeutic approach. In this study, we reported that octyl syr...

Alternative Titles

Full title

Octyl syringate is preferentially cytotoxic to cancer cells via lysosomal membrane permeabilization and autophagic flux inhibition

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2791422480

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2791422480

Other Identifiers

ISSN

0742-2091

E-ISSN

1573-6822

DOI

10.1007/s10565-021-09653-6

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