Microwave-assisted synthesis, spectroscopic characterization, and biological evaluation of fused thi...
Microwave-assisted synthesis, spectroscopic characterization, and biological evaluation of fused thieno[2,3-d]pyrimidines as potential anti-cancer agents targeting EGFRWT and EGFRT790M
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Publisher
Cham: Springer International Publishing
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Language
English
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Cham: Springer International Publishing
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Epidermal growth factor receptor (EGFR) is a transmembrane protein tyrosine kinase that is usually overexpressed in many types of cancers. In the present study, an effort was done in synthesis of new 3,4-diaminothieno[2,3-b] thiophene-2,5-dicarbonitrile derivatives
2–8
, assisted by a microwave device. Different spectroscopic instruments were...
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Full title
Microwave-assisted synthesis, spectroscopic characterization, and biological evaluation of fused thieno[2,3-d]pyrimidines as potential anti-cancer agents targeting EGFRWT and EGFRT790M
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TN_cdi_proquest_journals_2811080657
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2811080657
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ISSN
1381-1991
E-ISSN
1573-501X
DOI
10.1007/s11030-022-10477-7
