POS1272 INDUCTION OF REGULATORY T CELLS AND EFFICACY OF LOW DOSE INTERLEUKIN-2 IN SYSTEMIC SCLEROSIS...
POS1272 INDUCTION OF REGULATORY T CELLS AND EFFICACY OF LOW DOSE INTERLEUKIN-2 IN SYSTEMIC SCLEROSIS: INTERVENTIONAL OPEN-LABEL PHASE 1–PHASE 2A STUDY
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Publisher
Kidlington: BMJ Publishing Group Ltd and European League Against Rheumatism
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Language
English
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Publisher
Kidlington: BMJ Publishing Group Ltd and European League Against Rheumatism
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Contents
BackgroundSystemic sclerosis (SSc) is a chronic autoimmune disease, with impaired immune response, increased fibrosis, and endothelial dysfunction. (1,2) Regulatory T cells (Tregs), which are essential to prevent autoimmunity, showed a decreased frequency and impaired function during SSc. (3,4) Low-dose interleukin-2 (ld-IL2) can expand and activat...
Alternative Titles
Full title
POS1272 INDUCTION OF REGULATORY T CELLS AND EFFICACY OF LOW DOSE INTERLEUKIN-2 IN SYSTEMIC SCLEROSIS: INTERVENTIONAL OPEN-LABEL PHASE 1–PHASE 2A STUDY
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TN_cdi_proquest_journals_2821124986
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2821124986
Other Identifiers
ISSN
0003-4967
E-ISSN
1468-2060
DOI
10.1136/annrheumdis-2023-eular.1429
