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Hedgehog signaling regulates bone homeostasis through orchestrating osteoclast differentiation and o...

Hedgehog signaling regulates bone homeostasis through orchestrating osteoclast differentiation and o...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2821473121

Hedgehog signaling regulates bone homeostasis through orchestrating osteoclast differentiation and osteoclast–osteoblast coupling

About this item

Full title

Hedgehog signaling regulates bone homeostasis through orchestrating osteoclast differentiation and osteoclast–osteoblast coupling

Publisher

Cham: Springer International Publishing

Journal title

Cellular and molecular life sciences : CMLS, 2023-06, Vol.80 (6), p.171-171, Article 171

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

Imbalance of bone homeostasis induces bone degenerative diseases such as osteoporosis. Hedgehog (Hh) signaling plays critical roles in regulating the development of limb and joint. However, its unique role in bone homeostasis remained largely unknown. Here, we found that canonical Hh signaling pathway was gradually augmented during osteoclast diffe...

Alternative Titles

Full title

Hedgehog signaling regulates bone homeostasis through orchestrating osteoclast differentiation and osteoclast–osteoblast coupling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2821473121

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2821473121

Other Identifiers

ISSN

1420-682X,1420-9071

E-ISSN

1420-9071

DOI

10.1007/s00018-023-04821-9

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