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Melatonin protects against cisplatin-induced ovarian damage in mice via the MT1 receptor and antioxi...

Melatonin protects against cisplatin-induced ovarian damage in mice via the MT1 receptor and antioxi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2823839670

Melatonin protects against cisplatin-induced ovarian damage in mice via the MT1 receptor and antioxidant activity

About this item

Full title

Melatonin protects against cisplatin-induced ovarian damage in mice via the MT1 receptor and antioxidant activity

Publisher

United States: Society for the Study of Reproduction

Journal title

Biology of reproduction, 2017-06, Vol.96 (6), p.1244-1255

Language

English

Formats

Publication information

Publisher

United States: Society for the Study of Reproduction

More information

Scope and Contents

Contents

This study evaluated the receptor- and/or antioxidant stress-mediated mechanisms by which melatonin prevents the ovarian toxicity of cisplatin treatment. The expression of the MT1 receptor in mouse ovaries was investigated by immunohistochemistry. Pretreatment with melatonin (5, 10, or 20 mg/kg body weight, i.p.) before cisplatin (5 mg/kg body weig...

Alternative Titles

Full title

Melatonin protects against cisplatin-induced ovarian damage in mice via the MT1 receptor and antioxidant activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2823839670

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2823839670

Other Identifiers

ISSN

0006-3363

E-ISSN

1529-7268

DOI

10.1093/biolre/iox053

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