Design and preclinical evaluation of a novel apelin-based PET radiotracer targeting APJ receptor for...
Design and preclinical evaluation of a novel apelin-based PET radiotracer targeting APJ receptor for molecular imaging of angiogenesis
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Author / Creator
Louis, Béatrice , Nail, Vincent , Nachar, Oriane , Bouhlel, Ahlem , Moyon, Anaïs , Balasse, Laure , Simoncini, Stéphanie , Chabert, Adrien , Fernandez, Samantha , Brige, Pauline , Hache, Guillaume , Tintaru, Aura , Morgat, Clément , Dignat-George, Françoise , Garrigue, Philippe and Guillet, Benjamin
Publisher
Dordrecht: Springer Netherlands
Journal title
Language
English
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Publication information
Publisher
Dordrecht: Springer Netherlands
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Scope and Contents
Contents
APJ has been extensively described in the pathophysiology of angiogenesis and cell proliferation. The prognostic value of APJ overexpression in many diseases is now established. This study aimed to design a PET radiotracer that specifically binds to APJ. Apelin-F13A-NODAGA (AP747) was synthesized and radiolabeled with gallium-68 ([
68
Ga]Ga-A...
Alternative Titles
Full title
Design and preclinical evaluation of a novel apelin-based PET radiotracer targeting APJ receptor for molecular imaging of angiogenesis
Authors, Artists and Contributors
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Record Identifier
TN_cdi_proquest_journals_2834344056
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2834344056
Other Identifiers
ISSN
0969-6970,1573-7209
E-ISSN
1573-7209
DOI
10.1007/s10456-023-09875-8
