200 A unique CRISPR-based nuclease with a non-NGG PAM efficiently targets multiple exclusive genomic...
200 A unique CRISPR-based nuclease with a non-NGG PAM efficiently targets multiple exclusive genomic sites for immuno-oncology based therapy
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London: BMJ Publishing Group LTD
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English
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London: BMJ Publishing Group LTD
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BackgroundChimeric antigen receptor (CAR)-T cell therapy is a recent clinically successful approach to tackling cancer, in which T cells are genetically modified to allow specific recognition and efficient killing of cancer cells via tumor associated antigens.1 Current CAR-based treatments require costly and time-consuming autologous cell transfer....
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200 A unique CRISPR-based nuclease with a non-NGG PAM efficiently targets multiple exclusive genomic sites for immuno-oncology based therapy
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TN_cdi_proquest_journals_2834928647
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2834928647
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E-ISSN
2051-1426
DOI
10.1136/jitc-2022-SITC2022.0200
