1242 Altered interactions between circulating and tissue-resident CD8 T cells with the colonic mucos...
1242 Altered interactions between circulating and tissue-resident CD8 T cells with the colonic mucosa define checkpoint inhibitor colitis
About this item
Full title
Author / Creator
Slowikowski, Kamil , Thomas, Molly , Manakongtreecheep, Kasidet , Sen, Pritha , Tantivit, Jessica , Nasrallah, Mazen , Zubiri, Leyre , Smith, Neal , Tirard, Alice , Swetha Ramesh , Arnold, Benjamin , Nieman, Linda , Chen, Jonathan , Eisenhaure, Thomas , Pelka, Karin , Xu, Katherine , Jorgji, Vjola , Pinto, Christopher , Sharova, Tatyana , Glasser, Rachel , Chan, PuiYee , Sullivan, Ryan , Khalili, Hamed , Juric, Dejan , Boland, Genevieve , Dougan, Michael , Hacohen, Nir , Li, Bo , Reynolds, Kerry and Villani, Alexandra-Chloé
Publisher
London: BMJ Publishing Group LTD
Journal title
Language
English
Formats
Publication information
Publisher
London: BMJ Publishing Group LTD
Subjects
More information
Scope and Contents
Contents
BackgroundAntibodies targeting immune checkpoint inhibitors (ICIs) CTLA-4 and PD-1/PD-L1 have revolutionized the treatment of metastatic solid tumors. However, their use is limited by a high incidence of immune-related adverse events. The colon is a frequent target of this immune attack seen in up to 45% of patients on dual PD-1 and CTLA-4 blockade...
Alternative Titles
Full title
1242 Altered interactions between circulating and tissue-resident CD8 T cells with the colonic mucosa define checkpoint inhibitor colitis
Authors, Artists and Contributors
Author / Creator
Thomas, Molly
Manakongtreecheep, Kasidet
Sen, Pritha
Tantivit, Jessica
Nasrallah, Mazen
Zubiri, Leyre
Smith, Neal
Tirard, Alice
Swetha Ramesh
Arnold, Benjamin
Nieman, Linda
Chen, Jonathan
Eisenhaure, Thomas
Pelka, Karin
Xu, Katherine
Jorgji, Vjola
Pinto, Christopher
Sharova, Tatyana
Glasser, Rachel
Chan, PuiYee
Sullivan, Ryan
Khalili, Hamed
Juric, Dejan
Boland, Genevieve
Dougan, Michael
Hacohen, Nir
Li, Bo
Reynolds, Kerry
Villani, Alexandra-Chloé
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2835289750
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2835289750
Other Identifiers
E-ISSN
2051-1426
DOI
10.1136/jitc-2022-SITC2022.1242
