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970 Exhausted T cells are characterized by inappropriate lipid accumulation

970 Exhausted T cells are characterized by inappropriate lipid accumulation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2835510417

970 Exhausted T cells are characterized by inappropriate lipid accumulation

About this item

Full title

970 Exhausted T cells are characterized by inappropriate lipid accumulation

Publisher

London: BMJ Publishing Group LTD

Journal title

Journal for immunotherapy of cancer, 2022, Vol.10 (Suppl 2), p.A1012-A1012

Language

English

Publication information

Publisher

London: BMJ Publishing Group LTD

More information

Scope and Contents

Contents

BackgroundThe efficacy of immunotherapy depends on the presence and persistence of functional immune cells within the tumor. While tumor-specific T cells can be activated and infiltrate the tumor microenvironment, they are quickly rendered dysfunctional by the combination of chronic antigen stimulation, hypoxia, and nutrient stress that creates a u...

Alternative Titles

Full title

970 Exhausted T cells are characterized by inappropriate lipid accumulation

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2835510417

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2835510417

Other Identifiers

E-ISSN

2051-1426

DOI

10.1136/jitc-2022-SITC2022.0970

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