Engineering siRNA-loaded and RGDfC-targeted selenium nanoparticles for highly efficient silencing of...
Engineering siRNA-loaded and RGDfC-targeted selenium nanoparticles for highly efficient silencing of DCBLD2 gene for colorectal cancer treatment
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Publisher
Heidelberg: Springer Nature B.V
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Language
English
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Publisher
Heidelberg: Springer Nature B.V
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Scope and Contents
Contents
Effective and safe delivery of small interfering RNA (siRNA) by nanomaterials to cancer cells is one of the main challenges in cancer treatment. In this study, we constructed the selenium nanoparticles conjugated with RGDfC (one tumor-targeted polypeptide) to prepare a biocompatible gene vector (RGDfC-SeNPs) and then loaded with siDCBLD2 to synthes...
Alternative Titles
Full title
Engineering siRNA-loaded and RGDfC-targeted selenium nanoparticles for highly efficient silencing of DCBLD2 gene for colorectal cancer treatment
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TN_cdi_proquest_journals_2840417495
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2840417495
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ISSN
1931-7573
E-ISSN
1556-276X
DOI
10.1186/s11671-023-03870-0