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Engineering siRNA-loaded and RGDfC-targeted selenium nanoparticles for highly efficient silencing of...

Engineering siRNA-loaded and RGDfC-targeted selenium nanoparticles for highly efficient silencing of...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2840417495

Engineering siRNA-loaded and RGDfC-targeted selenium nanoparticles for highly efficient silencing of DCBLD2 gene for colorectal cancer treatment

About this item

Full title

Engineering siRNA-loaded and RGDfC-targeted selenium nanoparticles for highly efficient silencing of DCBLD2 gene for colorectal cancer treatment

Publisher

Heidelberg: Springer Nature B.V

Journal title

Nanoscale research letters, 2023-07, Vol.18 (1), p.94

Language

English

Formats

Publication information

Publisher

Heidelberg: Springer Nature B.V

More information

Scope and Contents

Contents

Effective and safe delivery of small interfering RNA (siRNA) by nanomaterials to cancer cells is one of the main challenges in cancer treatment. In this study, we constructed the selenium nanoparticles conjugated with RGDfC (one tumor-targeted polypeptide) to prepare a biocompatible gene vector (RGDfC-SeNPs) and then loaded with siDCBLD2 to synthes...

Alternative Titles

Full title

Engineering siRNA-loaded and RGDfC-targeted selenium nanoparticles for highly efficient silencing of DCBLD2 gene for colorectal cancer treatment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2840417495

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2840417495

Other Identifiers

ISSN

1931-7573

E-ISSN

1556-276X

DOI

10.1186/s11671-023-03870-0

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