1076 Anchored immunotherapy with intratumorally administered aluminum hydroxide-tethered IL-12 induc...
1076 Anchored immunotherapy with intratumorally administered aluminum hydroxide-tethered IL-12 induces potent anti-tumor immune response
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London: BMJ Publishing Group LTD
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English
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London: BMJ Publishing Group LTD
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BackgroundInterleukin-12 (IL-12) is a potent cytokine that can promote innate and adaptive anti-cancer immunity, but its clinical development has been limited by toxicity when delivered systemically.1 Intratumoral (IT) administration can expand the therapeutic window of IL-12 and other cytokines but is in turn limited by rapid clearance from the tu...
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1076 Anchored immunotherapy with intratumorally administered aluminum hydroxide-tethered IL-12 induces potent anti-tumor immune response
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TN_cdi_proquest_journals_2841226746
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2841226746
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E-ISSN
2051-1426
DOI
10.1136/jitc-2022-SITC2022.1076
