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p53 isoform expression promotes a stemness phenotype and inhibits doxorubicin sensitivity in breast...

p53 isoform expression promotes a stemness phenotype and inhibits doxorubicin sensitivity in breast...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2847568102

p53 isoform expression promotes a stemness phenotype and inhibits doxorubicin sensitivity in breast cancer

About this item

Full title

p53 isoform expression promotes a stemness phenotype and inhibits doxorubicin sensitivity in breast cancer

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2023-08, Vol.14 (8), p.509-16, Article 509

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

In breast cancer, dysregulated
TP53
expression signatures are a better predictor of chemotherapy response and survival outcomes than
TP53
mutations. Our previous studies have shown that high levels of Δ40p53 are associated with worse disease-free survival and disruption of p53-induced DNA damage response in breast cancers. Here, we furt...

Alternative Titles

Full title

p53 isoform expression promotes a stemness phenotype and inhibits doxorubicin sensitivity in breast cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2847568102

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2847568102

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/s41419-023-06031-4

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