NLRP3 monomer Functional Dynamics: from the Effects of Allosteric Binding to Implications for Drug D...
NLRP3 monomer Functional Dynamics: from the Effects of Allosteric Binding to Implications for Drug Design
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Ithaca: Cornell University Library, arXiv.org
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English
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Ithaca: Cornell University Library, arXiv.org
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The protein NLRP3 and its complexes are associated with an array of inflammatory pathologies, among which neurodegenerative, autoimmune, and metabolic diseases. Targeting the NLRP3 inflammasome represents a promising strategy for easing the symptoms of pathologic neuroinflammation. When the inflammasome is activated, NLRP3 undergoes a conformationa...
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NLRP3 monomer Functional Dynamics: from the Effects of Allosteric Binding to Implications for Drug Design
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TN_cdi_proquest_journals_2862629445
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2862629445
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E-ISSN
2331-8422
DOI
10.48550/arxiv.2309.03589
