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TRAF7-targeted HOXA5 acts as a tumor suppressor in prostate cancer progression and stemness via tran...

TRAF7-targeted HOXA5 acts as a tumor suppressor in prostate cancer progression and stemness via tran...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2877592796

TRAF7-targeted HOXA5 acts as a tumor suppressor in prostate cancer progression and stemness via transcriptionally activating SPRY2 and regulating MEK/ERK signaling

About this item

Full title

TRAF7-targeted HOXA5 acts as a tumor suppressor in prostate cancer progression and stemness via transcriptionally activating SPRY2 and regulating MEK/ERK signaling

Publisher

London: Nature Publishing Group UK

Journal title

Cell death discovery, 2023-10, Vol.9 (1), p.378-378, Article 378

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Homeobox A5 (HOXA5), a homeodomain transcription factor, is considered a tumor suppressor in cancer progression; however, its function in prostate cancer (PCa) remains unclear. This study focused on the relevance of HOXA5 in PCa progression. We identified the downregulation of HOXA5 in PCa tissues based on the TCGA database and further verified in...

Alternative Titles

Full title

TRAF7-targeted HOXA5 acts as a tumor suppressor in prostate cancer progression and stemness via transcriptionally activating SPRY2 and regulating MEK/ERK signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2877592796

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2877592796

Other Identifiers

ISSN

2058-7716

E-ISSN

2058-7716

DOI

10.1038/s41420-023-01675-9

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