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Determination of Metabolic Fluxes by Deep Learning of Isotope Labeling Patterns

Determination of Metabolic Fluxes by Deep Learning of Isotope Labeling Patterns

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2887141152

Determination of Metabolic Fluxes by Deep Learning of Isotope Labeling Patterns

About this item

Full title

Determination of Metabolic Fluxes by Deep Learning of Isotope Labeling Patterns

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2023-11

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Fluxomics offers a direct readout of metabolic state but relies on indirect measurement. Stable isotope tracers imprint flux-dependent isotope labeling patterns on metabolites we measure; however, the relationship between labeling patterns and fluxes remains elusive. Here we innovate a two-stage machine learning framework termed ML-Flux that stream...

Alternative Titles

Full title

Determination of Metabolic Fluxes by Deep Learning of Isotope Labeling Patterns

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2887141152

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2887141152

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2023.11.06.565907