Determination of Metabolic Fluxes by Deep Learning of Isotope Labeling Patterns
Determination of Metabolic Fluxes by Deep Learning of Isotope Labeling Patterns
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Fluxomics offers a direct readout of metabolic state but relies on indirect measurement. Stable isotope tracers imprint flux-dependent isotope labeling patterns on metabolites we measure; however, the relationship between labeling patterns and fluxes remains elusive. Here we innovate a two-stage machine learning framework termed ML-Flux that stream...
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Determination of Metabolic Fluxes by Deep Learning of Isotope Labeling Patterns
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TN_cdi_proquest_journals_2887141152
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2887141152
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E-ISSN
2692-8205
DOI
10.1101/2023.11.06.565907
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https://www.proquest.com/docview/2887141152?pq-origsite=primo&accountid=13902