O-GlcNAcylation determines the translational regulation and phase separation of YTHDF proteins
O-GlcNAcylation determines the translational regulation and phase separation of YTHDF proteins
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Author / Creator
Chen, Yulin , Wan, Ruixi , Zou, Zhongyu , Lao, Lihui , Shao, Guojian , Zheng, Yingying , Tang, Ling , Yuan, Ying , Ge, Yun , He, Chuan and Lin, Shixian
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
N
6
-methyladenosine (m
6
A) is the most abundant internal mRNA nucleotide modification in mammals, regulating critical aspects of cell physiology and differentiation. The YTHDF proteins are the primary readers of m
6
A modifications and exert physiological functions of m
6
A in the cytosol. Elucidating the regulatory mechan...
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Full title
O-GlcNAcylation determines the translational regulation and phase separation of YTHDF proteins
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TN_cdi_proquest_journals_2887724331
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2887724331
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ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/s41556-023-01258-x
